EFMC-ISCB 2023

EFMC International Symposium on Chemical Biology

Jointly organised with the Swiss Chemical Society, Division for Medicinal Chemistry & Chemical Biology (DMCCB)

 Basel, Switzerland    November 16-18, 2023

Programme


08:00

Registration

09:00

Opening Ceremony

Dr Yves P. AUBERSON
NOVARTIS & EFMC, Basel, Switzerland
Prof. Maja KÖHN
UNIVERSITY OF FREIBURG, Freiburg, Germany
09:15

Moving Undruggable Discoveries into the Drug Discovery Pipeline with Chemical Biology

Dr John TALLARICO
NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH, Cambridge, United States

Session 1: Chemical Proteomics in Drug Discovery

Session Chair

Dr Sebastian ESSIG
BAYER AG, Wuppertal, Germany
10:00

Title to be Announced

Dr Marcus BANTSCHEFF
CELLZOME/GSK, Heidelberg, Germany
10:45

Coffee Break, Networking & Exhibition

11:15

Towards Covalent Inhibitors Addressing Diverse Amino Acids

Dr Stephan HACKER
LEIDEN UNIVERSITY, Leiden, The Netherlands
11:40

ABPP and its Impact on Drug Discovery - Successful Examples from the MAGL Program

Dr Uwe GRETHER
F. HOFFMANN-LA ROCHE, Basel, Switzerland
12:05

Oral Communication 1

12:25

Lunch, Networking & Exhibition

Session 2: Computational Chemical Biology (LS-EuChemS Session)

Session Chair

Dr Sonsoles MARTIN-SANTAMARIA
CIB-CSIC, Madrid, Spain
13:55

Unravelling the Molecular Mechanism of Pre-mRNA Splicing via All-atom Simulations

Prof. Alessandra MAGISTRATO
CNR-IOM, Trieste, Italy
14:40

Challenges in Simulating Molecular Recognition Using Coarse-grain Models

Prof. Manuel MELO
UNIVERSITY NOVA DE LISBOA, Oeiras, Portugal
15:05

Oral Communication 2

15:30

Coffee Break, Networking & Exhibition

Session 3: Chemically Induced Proximity

Session Chair

Prof. Gonçalo BERNARDES
UNIVERSITY OF CAMBRIDGE & IMM LISBOA, Cambridge, United Kingdom
16:00

Oral Communication 3

16:20

Tumor Targeting

Prof. Dario NERI
ETH ZÜRICH, Zürich, Switzerland
16:45

Small Molecule Therapeutics Targeting Fibroblast Activation Protein in the Tumor Microenvironment

Dr Samuele CAZZAMALLI
PHILOCHEM AG, Otelfingen, Switzerland
17:10

Chemogenetic and Optogenetic Technologies for Probing Molecular and Cellular Networks (Virtual Lecture)

Prof. Alice TING
STANFORD UNIVERSITY, Stanford, United States
17:55

Poster Session I (Odd), Networking & Exhibition

19:30

Welcome Reception

21:00

End of the Day

09:00

Ribozymes Meet RNA Modifications


Prof. Claudia HÖBARTNER
UNIVERSITY OF WÜRZBURG, Würzburg, Germany

Session 4: Target Engagement and Mechanism of Action Determination

Session Chair

Dr Andrew ZHANG
ASTRAZENECA, Waltham, United States
09:45

Title to be Announced

Dr Rachel GRIMLEY
CANCER RESEARCH HORIZONS - THERAPEUTIC INNOVATION, Glasgow, United Kingdom
10:30

Coffee Break, Networking & Exhibition

11:00

Title to be Announced

Dr Mikhail SAVITSKY
EUROPEAN MOLECULAR BIOLOGY LABORATORY, Heidelberg, Germany
11:25

Proteomics Strategies for Characterizing Degraders and E3 Ligases

Dr Meha SINGH
ASTRAZENECA, Waltham, United States
11:50

Oral Communication 4

12:10

Lunch, Networking & Exhibition

Session 5: Protein Conformations: Beyond the Ground State

Session Chair

Dr Wolfgang JAHNKE
NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH, Basel, Switzerland
13:40

Title to be Announced

Prof. Dorothee KERN
BRANDEIS UNIVERSITY, Waltham, United States
14:25

Structure and Dynamics at Multiple Time Scales to Understand the Oncogenic kRas Cycle

Prof. Andras PERCZEL
EÖTVÖS LORÁND UNIVERSITY, Budapest, Hungary
14:50

Title to be Announced

Prof. Martin BLACKLEDGE
INSTITUT DE BIOLOGIE STRUCTURALE (IBS), Grenoble, France
15:15

Oral Communication 5

15:35

Coffee Break, Networking & Exhibition

Session 6: Targeting Metabolism (ICBS Session)

Session Chair

Prof. Zaneta NIKOLOVSKA-COLESKA
UNIVERSITY OF MICHIGAN, Ann Arbor, United States
16:05

Influence of Metabolism on Cancer

Prof. Matthew G. VANDER HEIDEN
MIT, Cambridge, United States
16:50

Chemical Biology of Sterol-mediated Processes

Dr Luca LARAIA
TECHNICAL UNIVERSITY OF DENMARK, Kgs. Lyngby, Denmark
17:15

Oral Communication 6

17:35

Poster Session II (Even), Networking & Exhibition

19:10

End of the Day

20:00

Symposium Banquet

09:00

Epigenetic Nucleobases in our Genome

Prof. Thomas CARELL
LUDWIG-MAXIMILIANS-UNIVERSITY, München, Germany

Session 7: Chemical Immunology & Checkpoint Inhibitors

Session Chair

Dr Sascha HOOGENDOORN
UNIVERSITY OF GENEVA, Geneva, Switzerland
09:45

Fluorescent Probes for Live-cell Imaging and Translational Studies

Prof. Marc VENDRELL
UNIVERSITY OF EDINBURGH, Edinburgh, United Kingdom
10:30

Coffee Break, Networking & Exhibition

11:00

Title to be Announced

Dr Kimberly BONGER
RADBOUD UNIVERSITY, Nijmegen, The Netherlands
11:25

Chemical Immunology Tools for Synthetic Adjuvant and Vaccine Development

Dr Alberto FERNÁNDEZ-TEJADA
CIC BIOGUNE, Derio (Bizkaia), Spain
11:50

Oral Communication 7

12:10

Lunch, Networking & Exhibition

Session 8: New Understandings of Post-translational Protein Modifications

Session Chair

Prof. Christian A. OLSEN
UNIVERSITY OF COPENHAGEN, Copenhagen, Denmark
13:40

Chemical Approaches to Studying Chromatin Regulation

Prof. Tom MUIR
PRINCETON UNIVERSITY, Princeton, United States
14:25

Beyond Phosphorylation – Protein Pyrophosphorylation by Inositol Pyrophosphate Messengers

Prof. Dorothea FIEDLER
LEIBNIZ-FORSCHUNGSINSTITUT FÜR MOLEKULARE PHARMAKOLOGIE (FMP), Berlin, Germany
14:50

Title to be Announced

Prof. Beat FIERZ
ECOLE POLYTECHNIQUE FÉDÉRALE DE LAUSANNE, Lausanne, Switzerland
15:15

Oral Communication 8

15:35

Coffee Break, Networking & Exhibition

Session 9: EFMC-WuXi AppTec Award for Excellence in Chemical Biology

Session Chair

Prof. Rui MOREIRA
UNIVERSITY OF LISBON, Lisbon, Portugal
16:05

Award Ceremony

16:20

EFMC-WuXi AppTec Award for Excellence in Chemical Biology Lecture:
Translational Chemical Biology

Prof. Gonçalo BERNARDES
UNIVERSITY OF CAMBRIDGE & IMM LISBOA, Cambridge, United Kingdom
17:05

Poster Prizes Ceremony

17:20

Closing Remarks

Dr Yves P. AUBERSON
NOVARTIS & EFMC, Basel, Switzerland
17:25

End of the Symposium


Printer friendly version