EFMC-ISCB 2023

EFMC International Symposium on Chemical Biology

Jointly organised with the Swiss Chemical Society, Division for Medicinal Chemistry & Chemical Biology (DMCCB)

 Basel, Switzerland    November 16-18, 2023

Plenary Speakers

PL02 - Ribozymes Meet RNA Modifications

Prof. Claudia HÖBARTNER
Prof. Claudia HÖBARTNER
UNIVERSITY OF WÜRZBURG, Würzburg, Germany
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PL04 - EFMC-WuXi AppTec Award for Excellence in Chemical Biology Lecture:
Translational Chemical Biology

Prof. Gonçalo BERNARDES
Prof. Gonçalo BERNARDES
UNIVERSITY OF CAMBRIDGE & IMM LISBOA, Cambridge, United Kingdom
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PL03 - The Second Dimension of the Genetic Code

Prof. Thomas CARELL
Prof. Thomas CARELL
LUDWIG-MAXIMILIANS-UNIVERSITY, München, Germany
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PL01 - Moving Undruggable Discoveries into the Drug Discovery Pipeline with Chemical Biology

Dr John TALLARICO
Dr John TALLARICO
NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH, Cambridge, United States
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Keynote Speakers

KL01 - Chemoproteomics Approaches and their Contributions to Drug Discovery

Dr Marcus BANTSCHEFF
Dr Marcus BANTSCHEFF
CELLZOME/GSK, Heidelberg, Germany
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KL04 - Mechanistic Insight in Drug Discovery: Past Tense of Future Direction? (Virtual Lecture)

Dr Rachel GRIMLEY
Dr Rachel GRIMLEY
CANCER RESEARCH HORIZONS (CANCER RESEARCH UK), Cambridge, United Kingdom
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KL05 - Evolution of Energy Landscapes and its Exploitation for Drug and Enzyme Design

Prof. Dorothee KERN
Prof. Dorothee KERN
BRANDEIS UNIVERSITY, Waltham, United States
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KL02 - Unravelling the Molecular Mechanism of Pre-mRNA Splicing via All-atom Simulations

Prof. Alessandra MAGISTRATO
Prof. Alessandra MAGISTRATO
CNR-IOM, Trieste, Italy
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KL08 - Chemical Approaches to Studying Chromatin

Prof. Tom MUIR
Prof. Tom MUIR
PRINCETON UNIVERSITY, Princeton, United States
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KL03 - Chemogenetic and Optogenetic Technologies for Probing Molecular and Cellular Networks (Virtual Lecture)

Prof. Alice TING
Prof. Alice TING
STANFORD UNIVERSITY, Stanford, United States
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KL06 - Understanding the Role of Metabolism in Cancer

Prof. Matthew G. VANDER HEIDEN
Prof. Matthew G. VANDER HEIDEN
MIT, Cambridge, United States
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KL07 - Fluorescent Amino Acids and Peptides for Translational Imaging of Infection and Inflammation in Humans

Prof. Marc VENDRELL
Prof. Marc VENDRELL
UNIVERSITY OF EDINBURGH, Edinburgh, United Kingdom
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Invited Speakers

IL09 - NMR Provides Unique Insight into the Role of Disorder in Highly Dynamic Viral Replication Assemblies

Prof. Martin BLACKLEDGE
Prof. Martin BLACKLEDGE
INSTITUT DE BIOLOGIE STRUCTURALE (IBS), Grenoble, France
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IL11 - Chemoenzymatic and Metabolic Protein Labeling Strategies

Dr Kimberly BONGER
Dr Kimberly BONGER
RADBOUD UNIVERSITY, Nijmegen, The Netherlands
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IL05 - Small Molecule Therapeutics Targeting Fibroblast Activation Protein in the Tumor Microenvironment

Dr Samuele CAZZAMALLI
Dr Samuele CAZZAMALLI
PHILOCHEM AG, Otelfingen, Switzerland
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IL12 - Chemical Immunology Tools for Synthetic Adjuvant and Vaccine Development

Dr Alberto FERNÁNDEZ-TEJADA
Dr Alberto FERNÁNDEZ-TEJADA
CIC BIOGUNE, Derio (Bizkaia), Spain
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IL13 - Beyond Phosphorylation – Protein Pyrophosphorylation by Inositol Pyrophosphate Messengers

Prof. Dorothea FIEDLER
Prof. Dorothea FIEDLER
LEIBNIZ-FORSCHUNGSINSTITUT FÜR MOLEKULARE PHARMAKOLOGIE (FMP), Berlin, Germany
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IL14 - Decoding PTM Signaling from Chromatin to the Cytoskeleton

Prof. Beat FIERZ
Prof. Beat FIERZ
ECOLE POLYTECHNIQUE FÉDÉRALE DE LAUSANNE, Lausanne, Switzerland
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IL02 - ABPP and its Impact on Drug Discovery - Successful Examples from the MAGL Program

Dr Uwe GRETHER
Dr Uwe GRETHER
F. HOFFMANN-LA ROCHE, Basel, Switzerland
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IL01 - Towards Covalent Inhibitors Addressing Diverse Amino Acids

Dr Stephan HACKER
Dr Stephan HACKER
LEIDEN UNIVERSITY, Leiden, The Netherlands
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IL10 - Chemical Biology of Sterol-mediated Processes

Dr Luca LARAIA
Dr Luca LARAIA
TECHNICAL UNIVERSITY OF DENMARK, Kgs. Lyngby, Denmark
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IL03 - Challenges in Simulating Molecular Recognition Using Coarse-grain Models

Prof. Manuel MELO
Prof. Manuel MELO
UNIVERSITY NOVA DE LISBOA, Oeiras, Portugal
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IL04 - Tumor Targeting

Prof. Dario NERI
Prof. Dario NERI
ETH ZÜRICH, Zürich, Switzerland
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IL06 - Biophysical Proteomics

Dr Mikhail SAVITSKY
Dr Mikhail SAVITSKY
EUROPEAN MOLECULAR BIOLOGY LABORATORY, Heidelberg, Germany
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IL07 - Proteomics Profiling of PROTACs and E3 Modulators to Identify Mechanistic Biomarkers and Substrates

Dr Meha SINGH
Dr Meha SINGH
ASTRAZENECA, Waltham, United States
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IL08 - Low Molecular Weight Inhibitors of IL-1β: from a 19F NMR Fragment Hit to a Cellular Proof of Concept

Dr Anna VULPETTI
Dr Anna VULPETTI
NOVARTIS, Basel, Switzerland
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Oral Communications

OC05 - Spatiotemporally Controlled Generation of NTPs as A Versatile Tool for Single-Molecule Studies

Prof. Sebastian DEINDL
Prof. Sebastian DEINDL
UPPSALA UNIVERSITY, Uppsala, Sweden
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OC03 - Molecular Glues for the 14-3-3 Interactome

Dr Richard DOVESTON
Dr Richard DOVESTON
UNIVERSITY OF LEICESTER, Leicester, United Kingdom
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OC06 - The Hidden Activator Within the Inhibitor: Regulated Tissue-Selective Inhibition and Activation of the Sugar Tolerance Transcription Factor ChREBP

Dr Maren HEIMHALT
Dr Maren HEIMHALT
LUDWIG MAXIMILIAN UNIVERSITÄT, Planegg-Martinsried, Germany
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OC07 - Collectin-11 Antagonists in a Therapeutic Approach to Minimize Complement-Mediated Immune Injury

Dr Rachel HEVEY
Dr Rachel HEVEY
UNIVERSITY OF BASEL, Basel, Switzerland
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OC02 - Molecular Binding Studies in G Protein Coupled Receptors: Insights for Drug Discovery

Prof. Vittorio LIMONGELLI
Prof. Vittorio LIMONGELLI
UNIVERSITÀ DELLA SVIZZERA ITALIANA USI, Lugano, Switzerland
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OC01 - Lessons for Covalent Drug Development from Deep Chemoproteomic Profiling of Approved Covalent Drugs

Dr Micah NIPHAKIS
Dr Micah NIPHAKIS
LUNDBECK, San Diego, CA, United States
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OC08 - PhotoCrot: a Precise Photo-Chemical Approach to Selectively Identify Crotonylated Proteins

Dr Rita PETRACCA
Dr Rita PETRACCA
UTRECHT UNIVERSITY, Utrecht, The Netherlands
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OC04 - Morphological Profiling of Small Molecules Using the Cell Painting Assay

Dr Slava ZIEGLER
Dr Slava ZIEGLER
MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY, Dortmund, Germany
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